Peptides containing disulfide bridges
For peptides comprising several cysteines it is always difficult to ensure the correct disulfide ligation.
Using a number of different cysteine protecting groups during synthesis plus decades of knowhow in correct folding conditions for bridged peptides, PANATecs is capable of synthesising peptides containing complex bridges.
An application would be for example using peptides containing disulfide bridges/bonds as reference substances in mass spectrometry-based quality control of biologics or biosimilars.